Cruises to South America are generally available from November until April in order to take advantage of the South American summer. A wide range of cruise lines offer South America cruises including Costa Cruises, Celebrity Cruises, Holland America Line, Norwegian Cruise Line (NCL), Princess Cruises, Regent Seven Seas, Seabourn Cruise Line, Silversea Cruises. Choose your cruise itinerary carefully if you would like Antartica included on your cruise to South America.